Brock Purdy: Which games could 49ers quarterback miss with toe injury?

The San Francisco 49ers, a storied franchise in the NFL, have always been known for their resilience in the face of adversity. However, the start of the 2025 NFL season has presented them with a new challenge in the form of significant injury issues. The team’s thrilling 17-13 victory over the Seattle Seahawks in their season opener was marred by the loss of star tight end George Kittle to a hamstring injury.

Kittle, one of the most dynamic and impactful players on the 49ers roster, was forced to leave the game in the second quarter after pulling up lame while running a route. The injury was a devastating blow to the team, as Kittle’s presence on the field is not only crucial for their offensive success but also serves as a rallying point for his teammates.

As news of Kittle’s injury spread, the mood in the 49ers’ locker room was somber. Head coach Kyle Shanahan addressed the team, urging them to stay focused and not let Kittle’s absence derail their season. The players, while visibly shaken by the loss of their teammate, vowed to come together and overcome this adversity.

However, Kittle’s injury was not the only setback the 49ers faced in their season opener. Starting quarterback Jimmy Garoppolo also suffered a sprained ankle in the third quarter, further complicating the team’s situation. With both Kittle and Garoppolo sidelined, the 49ers were forced to rely on backup quarterback Trey Lance to lead them to victory.

Lance, a rookie quarterback selected in the first round of the 2025 NFL Draft, showed flashes of brilliance in relief of Garoppolo. His poise under pressure and ability to make plays with his legs kept the 49ers in the game and ultimately led them to victory. However, the team knew that they would need more than just a stellar performance from their rookie quarterback to navigate the challenges ahead.

In the days following their season opener, the 49ers’ medical staff worked tirelessly to assess the extent of Kittle and Garoppolo’s injuries. The news was not promising, as both players were ruled out indefinitely. The team was faced with the daunting task of moving forward without two of their key offensive weapons.

As the 49ers prepared for their next game against the Los Angeles Rams, the mood around the team was one of determination and resolve. The players knew that they would have to step up in the absence of Kittle and Garoppolo and that every member of the team would need to contribute in order to fill the void left by their injured teammates.

In a show of solidarity, the 49ers’ defense stepped up in a big way against the Rams. Led by defensive end Nick Bosa, the defense held the high-powered Rams’ offense in check and forced multiple turnovers. Bosa, who was coming off a season-ending injury of his own the previous year, showed no signs of rust as he terrorized Rams quarterback Matthew Stafford all game long.

The offense, meanwhile, struggled to find its rhythm without Kittle and Garoppolo. Lance, while showing flashes of potential, also made rookie mistakes that cost the team crucial points. The running game, usually a strength for the 49ers, was stymied by the Rams’ stout defense, leaving the team with few options to move the ball downfield.

Despite their best efforts, the 49ers ultimately fell to the Rams by a score of 24-20. The loss was a bitter pill to swallow for a team that had shown so much resilience in the face of adversity. However, the players refused to dwell on the defeat, instead choosing to focus on the positives and the lessons they could take away from the game.

As the season progressed, the 49ers continued to face challenges on and off the field. Injuries continued to plague the team, with key players like linebacker Fred Warner and wide receiver Deebo Samuel also missing time due to various ailments. The coaching staff was forced to shuffle the lineup on a weekly basis, trying to find the right combination of players to keep the team competitive.

Despite the setbacks, the 49ers never lost sight of their ultimate goal: to win a championship. The players continued to work tirelessly in practice, pushing each other to be better and never giving up on each other. The team’s camaraderie and unity were on full display, as players rallied around each other in times of adversity and celebrated each other’s successes.

As the regular season drew to a close, the 49ers found themselves in a tight race for a playoff spot. With a record of 9-7, the team needed a win in their final game against the Arizona Cardinals to secure a spot in the postseason. The stakes could not have been higher, and the players knew that they would have to bring their best effort to come out on top.

In a thrilling back-and-forth game, the 49ers emerged victorious over the Cardinals by a score of 27-24. The win secured a playoff berth for the team and sparked celebrations among players and fans alike. Despite the adversity they had faced throughout the season, the 49ers had persevered and earned the right to compete for a championship.

As they prepared for their first playoff game against the Green Bay Packers, the 49ers were once again faced with injury concerns. Kittle and Garoppolo had both returned to practice, but their availability for the game was still uncertain. The team knew that they would need all hands on deck to defeat the Packers, a formidable opponent with a potent offense led by quarterback Aaron Rodgers.

In a stunning turn of events, both Kittle and Garoppolo were cleared to play in the playoff game. Their presence on the field provided a much-needed boost to the team, as their leadership and playmaking ability were instrumental in the 49ers’ success. The offense finally clicked, with Garoppolo connecting with Kittle on multiple key plays that helped propel the team to victory.

The defense also rose to the occasion, stifling Rodgers and the Packers’ offense with a dominant performance. Bosa, Warner, and the rest of the defense wreaked havoc on the Packers’ offensive line, sacking Rodgers multiple times and forcing turnovers that swung the momentum in the 49ers’ favor.

In the end, the 49ers emerged victorious over the Packers by a score of 31-28, punching their ticket to the NFC Championship game. The win was a testament to the team’s resilience and determination, as they had overcome numerous obstacles throughout the season to reach this point. The players celebrated on the field, knowing that they were one step closer to achieving their ultimate goal.

As they prepared to face the Tampa Bay Buccaneers in the NFC Championship game, the 49ers knew that they would have their work cut out for them. The Buccaneers, led by future Hall of Fame quarterback Tom Brady, boasted one of the most potent offenses in the NFL and had a defense that could stymie even the most prolific offenses.

The game was a back-and-forth affair, with both teams trading blows throughout the contest. Garoppolo and Kittle once again proved to be the catalysts for the 49ers’ offense, connecting on several key plays that kept the team in the game. Lance also made crucial plays with his legs, extending drives and keeping the Buccaneers’ defense on its heels.

The

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Source: 101 Great Goals

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